Leptomycin B

Mfr.No.	SIH-534
Alternative Names	Elactocin, LMB, Mantuamycin, NSC 364372 ;
Appearance	Solution in ethanol (1 mg/ml)
Function	Nuclear export inhibitor
Inchi	1S/C33H48O6/c1-9-28(14-15-29-24(5)13-16-31(36)39-29)19-22(3)12-10-11-21(2)17-25(6)32(37)27(8)33(38)26(7)18-23(4)20-30(34)35/h10-11,13-17,19-20,22,24-27,29,33,38H,9,12,18H2,1-8H3,(H,34,35)/b11-10+,15-14+,21-17+,23-20+,28-19-/t22-,24+,25-,26+,27-,29-,33-/m1/s1
Inchikey	YACHGFWEQXFSBS-NRQIOVFOSA-N
Mode Of Action	Inhibitor
Molecular Formula	C33H48O6
Pubchem Cid	6917907
Research Area	Cancer ; Cancer Growth Inhibitors
Safety Phrases	Classification: B2 Flammable liquid - Flammable liquid D1B Toxic Material Causing Immediate and Serious Toxic Effects - Toxic by ingestion, Toxic by skin absorption Hazard statement(s): H225 Highly flammable liquid and vapour. H301 + H311 Toxic if swallowed or in contact with skin H315 Causes skin irritation. H319 Causes serious eye irritation. H331 Toxic if inhaled. H370 Causes damage to organs. Precautionary statement(s): P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ protective clothing. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P307 + P311 IF exposed: Call a POISON CENTER or doctor/ physician.
Smiles	CCC(/C=C/[C@H]1OC(=O)C=C[C@@H]1C)=C/[C@H](C)CC=CC(C)=C[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)CC(C)=CC(O)=O
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	87081-35-4
Molecular Weight	540.7
Scientific Background	Leptomycin B is an inhibitor of nuclear export proteins. It is an anti-fungal, and anti-tumor cytotoxin.
Solubility	May be dissolved into DMSO or ethanol. Use solutions made with DMSO within 24 hours.
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Shipping Temperature	Shipped Ambient
Gross Weight (kg)	0.25
Net Weight (g)	0.001
Purity	>99% (HPLC); NMR (Conforms)
Storage Temperature	-20ºC
Stock Product	Y

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900315-2	SIH-534-1MG	1 mg	$315		Add to Cart
BHB11900315-1	SIH-534-200UG	200 ug	$85		Add to Cart

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