GSK-3 inhibitor 3

Mfr.No.	T77342
Description	GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3alpha and GSK-3beta with IC50s of 0.35 nM and 0.25 nM, respectively.GSK-3 inhibitor 3 reduces the phosphorylation level of tau protein S396 with an IC50 of 10 nM in a triple transgenic mouse model of Alzheimer's disease. GSK-3 inhibitor 3 reduced the phosphorylation level of tau protein S396 in a triple transgenic mouse model of Alzheimer's disease, with an IC50 of 10 nM.GSK-3 inhibitor 3 can be used for the study of neurological diseases.
Molecular Formula	C23H15FN6O
Signaling Pathways	Stem Cells, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Smiles	N(C(=O)C1=NC(NC2=CC=C(CN)C=C2)=NC=C1)C=3C(=CC=NC3)C4=CC=C(F)C=C4
Cas Number	2227279-84-5
Molecular Weight	410.4
Target	Microtubule Associated, GSK-3

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SKU	Supplier No.	Size	Your price
BHB20442269	T77342	1 mg	$195	Add to Cart
BHB20442269	T77342	5 mg	$430	Add to Cart
BHB20442269	T77342	10 mg	$636	Add to Cart
BHB20442269	T77342	25 mg	$987	Add to Cart
BHB20442269	T77342	50 mg	$1360	Add to Cart
BHB20442269	T77342	100 mg	$1830	Add to Cart
BHB20442269	T77342	500 mg	$3680	Add to Cart