GSK-1070916

Mfr.No.	T6129
Description	GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
Alternative Names	GSK1070916
Molecular Formula	C30H33N7O
Signaling Pathways	Angiogenesis, Chromatin/Epigenetic, Cell Cycle/Checkpoint, Apoptosis, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling
Smiles	C(C)N1C=C(C(=N1)C2=CC=C(NC(N(C)C)=O)C=C2)C3=C4C(NC(=C4)C5=CC(CN(C)C)=CC=C5)=NC=C3
Cas Number	942918-07-2
Molecular Weight	507.63
Target	Tie-2, Aurora Kinase, AMPK, Apoptosis, FLT

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SKU	Supplier No.	Size	Your price
BHB20431325	T6129	1 mL	$108	Add to Cart
BHB20431325	T6129	1 mg	$41	Add to Cart
BHB20431325	T6129	5 mg	$96	Add to Cart
BHB20431325	T6129	10 mg	$162	Add to Cart
BHB20431325	T6129	25 mg	$278	Add to Cart
BHB20431325	T6129	50 mg	$437	Add to Cart
BHB20431325	T6129	100 mg	$648	Add to Cart