CU-T12-9

Mfr.No.	T15017
Description	CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-kappaB and invokes an elevation of the downstream effectors TNF-alpha, IL-10, and iNOS.
Molecular Formula	C17H13F3N4O2
Signaling Pathways	Immunology/Inflammation
Smiles	N(C)C1=C(C=C(N(=O)=O)C=C1)N2C=C(N=C2)C3=CC=C(C(F)(F)F)C=C3
Cas Number	1821387-73-8
Molecular Weight	362.31
Target	TLR

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SKU	Supplier No.	Size	Your price
BHB20408168	T15017	1 mL	$198	Add to Cart
BHB20408168	T15017	1 mg	$108	Add to Cart
BHB20408168	T15017	2 mg	$153	Add to Cart
BHB20408168	T15017	5 mg	$228	Add to Cart
BHB20408168	T15017	10 mg	$297	Add to Cart
BHB20408168	T15017	25 mg	$375	Add to Cart
BHB20408168	T15017	50 mg	$455	Add to Cart
BHB20408168	T15017	100 mg	$657	Add to Cart
BHB20408168	T15017	500 mg	$1360	Add to Cart