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CU-76

SKU : BHB20427283

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Description
Review(s)

Mfr.No.	T38329
Description	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 uM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-beta in THP-1 cells when used at concentrations of 10, 30, and 100 uM.
Molecular Formula	C11H8F2IN5O2
Signaling Pathways	Others
Smiles	N(C=1N=C(C(OC)=O)N=C(N)N1)C2=CC(F)=C(I)C(F)=C2
Cas Number	2400954-58-5
Molecular Weight	407.11
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20427283	T38329	5 mg	$695		Add to Cart

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CU-76

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