C8 D-threo Ceramide (d18:1/8:0)

Mfr.No.	T36322
Description	C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is cytotoxic to U937 cells (IC50 = 17 uM) and induces nuclear DNA fragmentation 5- to 6-fold more potently than C8 ceramide . C8 D-threo Ceramide is a substrate for E. coli diacylglycerol kinase. It activates ceramide-activated protein kinase (CAPK) in U937 cells. C8 D-threo Ceramide also enhances V. cholerae cytolysin pore formation in liposome lipid membranes, as measured by calcein release, with a 50% release dose (RD50) value of ~5 ug/ml.
Molecular Formula	C26H51NO3
Signaling Pathways	Others
Smiles	CCCCCCCCCCCCCC=C(CH)(O)(CH)(CO)NC(=O)CCCCCCC
Cas Number	175892-43-0
Molecular Weight	425.698
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20425642	T36322	1 mg	$325		Add to Cart