C2 L-threo Ceramide (d18:1/2:0)

Mfr.No.	T35927
Description	C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 uM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 uM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
Molecular Formula	C20H39NO3
Signaling Pathways	Others
Smiles	(CH)((CH)(/C=C/CCCCCCCCCCCCC)O)(NC(C)=O)CO
Cas Number	143615-69-4
Molecular Weight	341.53
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20425301	T35927	1 mg	$278		Add to Cart