C-021

Mfr.No.	T21870
Description	C 021 dihydrochloride is a potent CCR4 antagonist. C-021 (4-Quinazolinamine, 2-(1,4'-bipiperidin)-1'-yl-N-cycloheptyl-6,7-dimethoxy-) dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 nM, respectively. It effectively prevents human CCL22-derived (35S)GTPgammaS from binding to the receptor (IC50: 18 nM).
Alternative Names	C 021
Molecular Formula	C27H41N5O2
Signaling Pathways	Microbiology/Virology, Immunology/Inflammation
Smiles	N(C=1C2=C(N=C(N1)N3CCC(CC3)N4CCCCC4)C=C(OC)C(OC)=C2)C5CCCCCC5
Cas Number	864289-85-0
Molecular Weight	467.65
Target	CCR

Have you used this product?

SKU	Supplier No.	Size	Your price
BHB20411926	T21870	1 mL	$97	Add to Cart
BHB20411926	T21870	1 mg	$47	Add to Cart
BHB20411926	T21870	2 mg	$65	Add to Cart
BHB20411926	T21870	10 mg	$155	Add to Cart
BHB20411926	T21870	25 mg	$318	Add to Cart
BHB20411926	T21870	50 mg	$493	Add to Cart
BHB20411926	T21870	100 mg	$690	Add to Cart