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BMS-986251

SKU : BHB20428269

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Description
Review(s)

Mfr.No.	T40123
Description	BMS-986251 is a potent and specific RORgammat inverse agonist that exerts its action via oral administration. It shows an EC 50 of 12 nM for RORgammat GAL4. In human whole blood assay, BMS-986251 effectively inhibits IL-17 with an EC 50 of 24 nM. Furthermore, BMS-986251 exhibits strong therapeutic effects in mouse acanthosis and Imiquimod-induced models, which are commonly used preclinical models for psoriasis.
Molecular Formula	C30H29F8NO5S
Signaling Pathways	Others
Smiles	(H)(C)12CCc3cc(ccc3(C)1(CCN2C(=O)(CH)1CC(CH)(C(CH)1C)C(O)=O)S(=O)(=O)c1ccc(F)cc1)C(F)(C(F)(F)F)C(F)(F)F
Cas Number	2460133-35-9
Molecular Weight	667.61
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20428269	T40123	5 mg	$970		Add to Cart

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BMS-986251

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