AEW541 HCl

Mfr.No.	T69682
Description	AEW541, also known as NVP-AEW541, is a novel, potent IGF-IR kinase inhibitor. NVP-AEW541 is capable of distinguishing between the IGF-IR (IC50 = 0.086 microM) and the closely related InsR (IC50 = 2.3 microM) in cells. NVP- AEW541 abrogates IGF-I-mediated survival and colony formation in soft agar at concentrations that are consistent with inhibition of IGF-IR autophosphorylation. Note: AEW541 has a Cis-configuration on the cyclobutane ring. Its CAS# is 475489-16-8. Many vendors and Sc-finder scholar made mistake - AEW541 was mistakenly listed as CAS#475488-34-7, the trans-isomer of AEW541. The correct structure of AEW541 can be confirmed from Joel Slade, et al (from Novartis), Org. Process Res. Dev. 2007, 11, 5, 825835.
Molecular Formula	C27H31Cl2N5O
Signaling Pathways	Others
Cas Number	2320261-63-8
Molecular Weight	439.56
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20436938	T69682	1 mg	$293	Add to Cart
BHB20436938	T69682	5 mg	$1090	Add to Cart
BHB20436938	T69682	10 mg	$1910	Add to Cart
BHB20436938	T69682	500 ?g	$198	Add to Cart