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A-674563 HCl (552325-73-2(free base))

SKU : BHB20429247

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Description
Review(s)

Mfr.No.	T4444
Description	A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) (1). It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in the CMGC, CAMK, and TK families (1).
Molecular Formula	C22H23ClN4O
Signaling Pathways	Chromatin/Epigenetic, Cytoskeletal Signaling, Cell Cycle/Checkpoint, MAPK, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors
Cas Number	2070009-66-2
Molecular Weight	394.9
Target	CDK, PKA, PKC, Akt, ERK

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SKU	Supplier No.	Size	Your price
BHB20429247	T4444	1 mL	$140	Add to Cart
BHB20429247	T4444	1 mg	$77	Add to Cart
BHB20429247	T4444	2 mg	$111	Add to Cart

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A-674563 HCl (552325-73-2(free base))

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