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?-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE

SKU : BHB20444364

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Description
Review(s)

Mfr.No.	T80692
Description	beta-Glucuronide-NB-bis(N(Me)-methyl ester)-MMAE (compound 20), an auristatins-glucuronide conjugate, exhibits in vitro antiproliferative effects on cancer cells, both beta-glucuronidase pretreated and untreated, with an IC50 range of 5.7 nM to 9.7 nM. Demonstrating powerful antitumor efficacy in an HCT-116 xenograft mouse model, this compound does not induce side effects (1).
Signaling Pathways	Antibody-drug Conjugate/ADC Related, Others
Target	Others, Drug-Linker Conjugates for ADC

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SKU	Supplier No.	Size	Your price	Quantity
BHB20444364	T80692	5 mg	-		Add to Quote
BHB20444364	T80692	50 mg	-		Add to Quote

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?-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE

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