(±)5(6)-DiHET

Mfr.No.	T84609
Description	5(6)-DiHET is a racemic compound synthesized through the action of epoxide hydrolases on 5(6)-EET, encompassing both enantiomeric forms. It serves as a quantitative marker for 5(6)-EET, facilitating its measurement by utilizing the compound's conversion to 5(6)-delta-lactone in solution. Additionally, 5(6)-DiHET activates large-conductance calcium-activated potassium (KCa1.1/BK) channels in rat small coronary artery smooth muscle cells, supporting its biological significance in vascular regulation. It also acts as a substrate for sheep seminal vesicle COX, leading to the in vitro production of 5,6-dihydroxy prostaglandin E1 and F1alpha metabolites. Notably, its levels diminish in the plasma of rats subjected to a high-fat diet, indicating a potential role in the pathophysiology of hyperlipidemia.
Signaling Pathways	Others
Cas Number	213382-49-1
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20445880	T84609	10 mg	-		Add to Quote
BHB20445880	T84609	50 mg	-		Add to Quote