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Brain Case Biotech Co., Ltd
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Brain Case Biotech Co., Ltd
view supplier detailsCredit card payments now incur a 3% fee.
| Mfr.No. | BHS17100004 |
| Service Type | Neuroscientific Research |
| Service Specification | PRV |
| Provider | BrainCase |
| Provider Location | ShenZhen, PRC |
| Service ID/SKU | BHS17100004 |
| Description |
Polysynaptic Retrograde Tracing with Pseudorabies Virus at Braincase Unraveling Neural Circuits with Precision Braincase specializes in advanced polysynaptic retrograde tracing techniques using Pseudorabies Virus (PRV) to map complex neural circuits. Our tailored PRV-based tools enable researchers to dissect the intricate architecture of neural networks, providing insights into brain function and connectivity. Understanding PRV-Based Tracing Our PRV strains, derived from the less virulent Bartha strain, are engineered for strict retrograde labeling across multiple synapses. This allows for the detailed mapping of neural networks, identifying direct and indirect projections to targeted brain regions. Upon infecting neurons, the virus replicates and expresses the inserted gene, enabling the tracing of neural pathwa ys back to their origins.  Figure 1. PRV-Bartha strain reverse transpolysynaptic labeling  Figure 2. Injecting PRV into the brain area TU can mark the input neural network of different levels in the injection area. Applications of PRV Tracing Braincase's PRV tracing tools are invaluable for a variety of research applications, including:
Featured Case Studies
 Figure 3. Validation of R-NG→PBNdl→SNc pathway (HanW, et al., Cell, 2018)
 Figure 4. Identification of the M1L5 pyramidal neuron population in the upper bladder cortex (YaoJ, et al., NatNeurosc, 2018)
 Figure 5. Expression distribution of fluorescent proteins in different brain regions Braincase's PRV Product Offerings Our PRV tools come equipped with various fluorescent markers for easy visualization of traced pathways:
Explore Neural Networks with Braincase's PRV Tools Leverage Braincase's PRV-based tracing solutions to explore the depths of neural connectivity and function. Our tools are designed to facilitate groundbreaking discoveries in neuroscience research. Contact us for more information on our products and how we can support your research endeavors. |
| Keywords/Tags | Pseudorabies Virus, PRV, Polysynaptic Retrograde Tracing, Neural Circuit Mapping, Brain Function Analysis, Neuroscience Research |
| Geographic Availability | Global |
