This antibody reacts with the heavy chains of mouse IgG and with the light (kappa and lambda) chains common to most mouse immunoglobulins. The minimal cross-reaction with other species was ensured by pre-adsorption by agarose beads coupled with IgGs from Human, Goat, Rabbit, Bovine, Chicken, Guinea Pig, Syrian Hamster, Horse and Sheep Serum Proteins.