N1-Me-Pseudo UTP Tris Solution GMP grade (100 mM)

Mfr.No.

10657ES20, 10657ES80, 10657ES70

Description

N1-Me-Pseudo UTP solution is one of the most commonly used modified nucleoside triphosphates. It is mostly used as the reaction substrate or coenzyme of enzymes, such as in vitro transcription, RNA amplification, siRNA synthesis, etc. The modified mRNA containing pseudouridine has better nuclease stability and translation characteristics, and changes the innate immune receptor and in vitro transcription. The interaction of RNA has a wide range of applications in the field of therapy and diagnosis.

This product is produced in accordance with GMP process requirements and provided in liquid form.

Features

Validated, product-specific processes and analytical methods
Product-specific stability
Documentation follows applicable GMP guidelines
AOF production process and raw materials (TSE & BSE)
Nitrosamine statement
Regulatory support documents available
Large-scale production
The increased IVT yield and the decreased dsRNA content under the optimized Tris NTP reaction system

Molecular Formula

C₁₀H₁₇N₂O₁₅P₃ (free acid)

Specification

Components No.	Name	10657ES20	10657ES70	10657ES80	10657ES10	10657ES60
10657	N1-Me-Pseudo UTP Tris Solution GMP-grade (100 mM)	20 μL	100 μL	1 mL	10 mL	100 mL

Molecular Weight

498.17 g/moL (free acid)

Purity	≥ 99%
Storage	The product should be stored at -25℃ ~ -15℃ for two years.

Product Manual	Manual

Application	RNA synthesis and amplification Building block for in vitro transcription

Structure

Increased the IVT yield. The IVT yield was significantly increased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system.

Decreased the dsRNA content. The content of dsRNA was significantly decreased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system. The content of dsRNA was detected by the Dot Blot method.

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Combination SKU	Supplier No.	Size	Your price
BHN20800038-1	10657ES20	20uL	$205	Add to Cart
BHN20800038-2	10657ES80	1 mL	$2305	Add to Cart
BHN20800038-3	10657ES70	100uL	$790	Add to Cart

N1-Me-Pseudo UTP Tris Solution GMP grade (100 mM)

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