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Home / Primary Antibodies

RIP Antibody / RIPK1 (R31162)

SKU : BHA17104637

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NSJ Bioreagents

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Mfr.No.	R31162
Antigen	RIP
Clonality	Polyclonal
Description	Receptor-interacting serine/threonine-protein kinase 1 (RIPK1), also called RIP, is an enzyme that in humans is encoded by the RIPK1 gene. Members of the TRAF protein family have been implicated in the activation of NF-kappa-B by the TNF superfamily. By yeast 2-hybrid and coimmunoprecipitation studies using mammalian cell extracts, Hsu et al.(1996) showed that RIP interacts with TRADD, TRAF1, TRAF2, and TRAF3. Hartz(2012) mapped the RIPK1 gene to chromosome 6p25.2 based on an alignment of the RIP sequence with the genomic sequence. Stanger et al.(1995) found that overexpression of Rip in mammalian cells induced morphologic changes characteristic of apoptosis. They suggested that RIP may be an important element in the signal transduction machinery that mediates programmed cell death.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the middle region of human Receptor-interacting serine/threonine-protein kinase 1 (RRRRVSHDPFAQQRP) was used as the immunogen for this RIP antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q13546

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the RIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104637	R31162	100 ug	$419		Add to Cart

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