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Home / Proteins & Peptide

Recombinant Mouse MEK1 (EE) (N-GST tag)

SKU : BHP10901261

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z600015
Description	MEK1 (EE) is a member of the dual specificity protein kinase family that acts as a mitogen-activated protein kinase (MAPK) kinase. MEK1 lies upstream of MAPK/ERK and stimulates the enzymatic activity of MAPK/ERK upon a wide variety of extra- and intracellular signals. As an essential component of MAPK/ERK signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development . Constitutive activation of MEK1 results in cellular transformation. Thus, MEK1 represents a likely target for pharmacologic intervention in proliferative disease such as cancer .
Alternative Names	MAP2K1; MKK1; MAPKK1; PRKMK1
Appearance	Liquid
Formulation	50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Molecular Weight	69.0 kDa
Quantity	10 µg
Source	Insect cells
Usage	For research use only. Not for diagnostic or therapeutic use.
Accession Number	NM_008927
Bioactivity	The specific activity of MEK1 (EE) was determined to be 326 nmol /min/mg as per activity assay protocol.

Gene Name	MEK1

Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901261	Z600015	10µg	$314.44		Add to Cart

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