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Home / Proteins & Peptide

Recombinant Mouse Interleukin-1 receptor-like 2(Il1rl2),partial

SKU : BHP10503187

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP875357MO
Alternative Names	IL-36 receptor, Interleukin-1 receptor-related protein 2, IL-1Rrp2, IL1R-rp2, IL-36 receptor ; Interleukin-1 receptor-related protein 2 ; IL-1Rrp2 ; IL1R-rp2
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	22-338aa
Mol Weight	40.0kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Membrane, Single-pass type I membrane protein
Uniprot	Q9ERS7, Q9ERS7
Database Links	KEGG:mmu:107527 STRING:10090.ENSMUSP00000092630 UniGene:Mm.155583
Function	Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Protein Families	Interleukin-1 receptor family
Research Area	Immunology
Tissue Specificity	Expressed in bone marrow-derived dendritic cells, splenic CD4(+) T-cells, bone marrow-derived macrophages and bone marrow-derived neutrophils.
Weight	40.09kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503187	CSB-EP875357MO	1mg	$2466		Add to Cart
BHP10503187	CSB-EP875357MO	100ug	$729		Add to Cart
BHP10503187	CSB-EP875357MO	20ug	$388		Add to Cart

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