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Home / Proteins & Peptide

Recombinant Mouse IGF1/IGF?I/IGF-1 Protein

SKU : BHP10305219

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM040958
Description	A DNA sequence encoding the mouse IGF1 (NP_001104744.1) (Gly49-Ala118) was expressed.
Alternative Names	C730016P09Rik;Igf-1;Igf-I
Reconstitution	Please refer to the printed manual for detailed information.
Background	IGF I, also known as mechano growth factor, somatomedin-C, IGF-I and IGF1, is a secreted protein which belongs to the?insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ) and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of {1-14C}-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
Reactivity	Mouse
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	Yeast
Accession Number	NP_001104744.1
Endotoxin Level	Please contact us for more information.
Mol Weight	7.7 kDa
Mw(kda)	7.7 kDa

Sequence Info	Gly49-Ala118

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305219	PKSM040958	50ug	$281		Add to Cart

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