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Home / Proteins & Peptide

Recombinant Mouse HIPK2 (N-GST tag)

SKU : BHP10901256

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z600013
Description	HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors. HIPK2 enhances expression of p53 target genes that resulting in growth arrest and the enhancement of UV-induced apoptosis that could be inhibited by antisense to HIPK2 . HIPK2 as a target for MDM2 mediated ubiquitin-dependent degradation that only occurred in growth-arresting conditions when MDM2 was efficiently induced by p53 . The knockdown of HIPK2 using small interfering RNA reduced p53 binding and activation of p53R2 that resulting in impaired UV-induced DNA repair.
Alternative Names	Stank; 1110014O20Rik; B230339E18Rik
Appearance	Liquid
Formulation	50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Weight	72.0 kDa
Quantity	10 µg
Source	Insect cells
Usage	For research use only. Not for diagnostic or therapeutic use.
Accession Number	BC031904
Bioactivity	The specific activity of HIPK2 was determined to be 110 nmol /min/mg as per activity assay protocol.

Gene Name	HIPK2

Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901256	Z600013	10µg	$314.44		Add to Cart

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