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Home / Proteins & Peptide

Recombinant IL-12, Mouse

SKU : BHP11300194

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Mfr.No.	BK0230‐10μg
Description	Interleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes, macrophages, B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex, which is comprised of IL-12 Rβ1 and IL-12 Rβ2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells and T- cells. It is indispensible during the development of Th1 cells, leading to the production of IFN-gamma and IL-2.
Alternative Names	Interleukin-12 ; IL12
Regulatory	RUO
Source	CHO
Host	Mouse
Endotoxin Level	< 0.2 EU/μg, determined by LAL method.
Biological Activity Comment	ED50 < 0.15 ng/ml, measured in a cell proliferation assay using 2D6 cells.
Nature	Recombinant

Weight	27-29 kDa (p35) and 45-50 kDa (p40), observed by reducing SDS-PAGE.

Description	Reconstituted in ddH2O or PBS at 100 μg/ml.
Format	Lyophilized after extensive dialysis against PBS. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 95% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant murineInterleukin-12 (IL-12), remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, murine Interleukin-12 (IL-12), His should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300194	BK0230‐10μg	10μg	$252.67		Add to Cart
BHP11300194	BK0230‐10μg	1mg	$5788.89		Add to Cart
BHP11300194	BK0230‐10μg	50μg	$730		Add to Cart

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