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Home / Proteins & Peptide

Recombinant Human PIP5K1C (N-GST tag)

SKU : BHP10900910

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500306
Description	PIP5K1C or phosphatidylinositol-4-phosphate 5-kinase 1 gamma phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1C is found at synapses and has been found to play roles in endocytosis and cell migration. PIP5K1C directly associates with ß-catenin and increases ß-catenin activity downstream of growth factor stimulation . PIP5K1C expression and kinase activity enhance ß-catenin phosphorylation on residues that promote nuclear importation and transcriptional activity. PIP5K1C deficiency impairs neutrophil recruitment as a result of defect in adhesion. PIP5K1C regulated the adhesion through facilitating RhoA GTPase and integrin activation by chemoattractants .
Alternative Names	LCCS3 ; PIP5K-GAMMA ; PIP5Kgamma ; PIPKIg_v4 ; KIAA0589
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PIP5K1C was determined to be 220 nmol /min/mg as per activity assay protocol.

Weight	120.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900910	Z500306	10µg	$361.11		Add to Cart

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