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Home / Proteins & Peptide

Recombinant Human PI3K (p120 gamma) (N-His tag)

SKU : BHP10900150

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500293
Description	PI3K (p120?) is a member of the PI3K family that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. PI3K (p120?) is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, PI3K (p120?) is thought to play a pivotal role in the regulation of cytotoxicity in NK cells . In addition, PI3K (p120?) plays an inhibitory role in inflammatory mediator-induced human vascular smooth muscle cell calcification through regulating alkaline phosphatase expression .
Alternative Names	p110γ: PI3K ; PIK3 ; PI3CG ; PI3Kgamma
Tag	N-His tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PI3K (p120?) was determined to be 52 nmol/min/mg as per activity assay protocol.

Weight	121.0 kDa

Format	Liquid 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900150	Z500293	10µg	$261.11		Add to Cart

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