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Home / Proteins & Peptide

Recombinant Human PI3K (p110 beta/p85 beta) (N-His tag)

SKU : BHP10900917

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500291
Description	PI3K phosphorylate the 3-prime OH position of the inositol ring of inositol lipids which functions in signaling pathways that regulate cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kDa catalytic subunit and a 85-kDa adaptor subunit . PI3K plays a critical role in regulating the formation and stability of alpha-2B-beta-3 integrin adhesion bonds, which are necessary for shear force-induced platelet activation. PI3K sustains alpha-2B-beta-3 integrin activation and stabilized platelet aggregation by regulating both integrin-dependent calcium flux and Gi activation of RAP1B .
Alternative Names	p110-BETA ; DKFZp779K1237 ; p110ÃŽÂ²: PI3K ; PIK3C1 ; PI3Kbeta ; MGC133043
Tag	N-His tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PI3K was determined to be 28 nmol /min/mg as per activity assay protocol.

Weight	88.0 kDa, 111.0 kDa

Format	Liquid 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900917	Z500291	10µg	$361.11		Add to Cart

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