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Home / Proteins & Peptide

Recombinant Human PI3K (p110 alpha/p55 gamma) (N-His tag)

SKU : BHP10901225

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500288
Description	PI3K (p110alpha/p55gamma) or Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position which serve as second messengers in growth signaling pathways. PI3K comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in the PI3K has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo . PI3K also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses .
Alternative Names	p110a: PI3K ; p110-alpha
Tag	N-His tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PI3K(p110a/p55?)wasdetermined to be 14 nmol /min/mg as per activity assay protocol.

Weight	61.0 kDa, 111.0 kDa

Format	Liquid 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901225	Z500288	10µg	$361.11		Add to Cart

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