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Home / Primary Antibodies / Monoclonal Antibodies

Mono-methyl-Histone H3.1?R2?Antibody

SKU : BHA10560706

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-RA010418A02me1HU
Alternative Names	Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, H3FA, AND, HIST1H3B, H3FL, AND, HIST1H3C, H3FC, AND, HIST1H3D, H3FB, AND, HIST1H3E, H3FD, AND, HIST1H3F, H3FI, AND, HIST1H3G, H3FH, AND, HIST1H3H, H3FK, AND, HIST1H3I, H3FF, AND, HIST1H3J, H3FJ
Categories	Primary Antibodies
Clonality	monoclonal
Description	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Host	Rabbit
Immunogen	A synthesized peptide
Involvement In Disease	Glioma (GLM)
Isotype	IgG
Reactivity	Human
Regulatory	RUO
Relevance	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Chromosome

Uniprot	P68431
Gene Id	8350
Gene Name	HIST1H3A
Database Links	HGNC:4766 OMIM:137800 KEGG:hsa:8350 STRING:9606.ENSP00000444823 UniGene:Hs.132854
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Families	Histone H3 family
Research Area	Epigenetics and Nuclear Signaling
Weight	15,404 Da

Buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Liquid
Format	Liquid
Purification	Affinity-chromatography
Purity	Affinity-chromatography
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Applications

ELISA, WB, ICC, IF

Description

ELISA ; WB ; ICC ; IF, WB ; ELISA ; ICC ; IF

Dilution

WB	1:500-1:2000
ICC	1:50-1:500
IF	1:30-1:200

Tested Application

ELISA, WB, ICC, IF; Recommended dilution: WB:1:500-1:2000, ICC:1:50-1:500, IF:1:30-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560706	CSB-RA010418A02me1HU	100ul	$350		Add to Cart
BHA10560706	CSB-RA010418A02me1HU	50ul	$210		Add to Cart

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