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Home / Primary Antibodies / Recombinant Antibodies

Hydroxyl-Histone H2A type 1-B/E (Y39) Antibody

SKU : BHA10560703

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-RA010385A39ohHU
Alternative Names	Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, HIST1H2AB, H2AFM, AND, HIST1H2AE, H2AFA
Categories	Primary Antibodies
Clonality	monoclonal
Description	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Host	Rabbit
Immunogen	A synthesized peptide
Isotype	IgG
Reactivity	Human
Regulatory	RUO
Relevance	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Chromosome

Uniprot	P04908
Gene Id	3012
Gene Name	HIST1H2AB
Database Links	HGNC:4734 OMIM:602786 KEGG:hsa:3012 STRING:9606.ENSP00000303373 UniGene:Hs.121017
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Families	Histone H2A family
Research Area	Epigenetics and Nuclear Signaling
Weight	14 kDa

Buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Liquid
Format	Liquid
Purification	Affinity-chromatography
Purity	Affinity-chromatography
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:2000

Tested Application

ELISA, WB; Recommended dilution: WB:1:500-1:2000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560703	CSB-RA010385A39ohHU	100ul	$350		Add to Cart
BHA10560703	CSB-RA010385A39ohHU	50ul	$210		Add to Cart

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