Estrogen Receptor alpha delta 4*5,6,7*/654 isoform ; Estrogen Receptor alpha delta 4 +49 isoform ; Nuclear receptor subfamily 3 group A member 1
Categories
Primary Antibodies
Cellular Localization
Nuclear
Chromosome Location
6q25.1
Clonality
monoclonal
Description
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.
Host
Rabbit
Immunogen
Recombinant full-length human Estrogen Receptor alpha protein
Isotype
IgG
Positive Control
MCF-7 Cells or Breast Cancers.
Reactivity
Human
Recombinant
TRUE
Regulatory
RUO
Species
Homo Sapiens (Human)
Swissprot
P03372
Gene Id
2099
Clone No
ESR1, 2299R
Symbol
ESR1
Weight
~67kDa
Buffer
200μg/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Applications
IHC-F
Description
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IHC-F
Dilution
Immunohistology (Formalin-fixed)
1-2μg/ml for 30 minutes at RT
No Description Available.
No Description Available.
Reviews of Anti-undefined Antibody ESR1,2299R Unconjugated BHA10208206