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Home / Primary Antibodies / Recombinant Antibodies

Anti-RAD9A Antibody BHA11309103

SKU : BHA11309103

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Mfr.No.	MB0162
Alternative Names	Cell cycle checkpoint control protein ; DNA repair exonuclease rad9 homolog A ; hRAD 9 ; hRAD9 ; Rad 9 ; RAD 9A ; RAD9 (S pombe) homolog ; RAD9 homolog A ; RAD9 homolog ; RAD9A ; RAD9
Antigen	RAD9A
Categories	Primary Antibodies
Chromosome Location	11q13.2
Clonality	monoclonal
Description	Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair.The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C(RFC)clamp loader complex.Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair(LP-BER).The 9-1-1 complex stimulates DNA polymerase beta(POLB)activity by increasing its affinity for the 3´-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds;endonuclease FEN1 cleavage activity on substrates with double,nick,or gap flaps of distinct sequences and lengths;and DNA ligase I(LIG1)on long-patch base excision repair substrates.The 9-1-1 complex is necessary for the recruitment of C12orf32/RHINO to sites of double-stranded breaks(DSB)occurring during the S phase.RAD9A possesses 3´->5´ double stranded DNA exonuclease activity.Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.
Host	Mouse
Immunogen	Recombinant full length Human RAD9A.
Reactivity	Human, Mouse, Rat, Monkey
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q99638
Uniprot	Q99638
Weight	Predicted band size:43KDaObserved band size:55KDa

Description	Product: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol Specificity: This antibody detects endogenous levels of RAD9A and does not cross-react with related proteins
Purity	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IP

Description

WB ; IP

Dilution

WB	1:500-1000
IP	1:50-100

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11309103	MB0162	50µl	$234.89		Add to Cart
BHA11309103	MB0162	100µl	$368.22		Add to Cart

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