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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CBR1 Antibody BHA11309062

SKU : BHA11309062

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Mfr.No.	MB0121
Alternative Names	15 hydroxyprostaglandin dehydrogenase [NADP+] ; 15-hydroxyprostaglandin dehydrogenase [NADP+] ; Carbonyl reductase [NADPH] 1 ; Carbonyl Reductase 1 ; CBR 1 ; CBR1 ; CBR1 ; CRN ; NADPH dependent carbonyl reductase 1 ; NADPH-dependent carbonyl reductase 1 ; Prostaglandin 9 ketoreductase ; Prostaglandin 9-ketoreductase ; Prostaglandin E(2) 9 reductase ; Prostaglandin-E(2) 9-reductase ; SDR21C1 ; CBR ; hCBR1 ; SDR21C1
Categories	Primary Antibodies
Chromosome Location	21q22.12
Clonality	monoclonal
Description	Carbonyl reductase is one of several monomeric,NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds.This enzyme is widely distributed in human tissues. Another carbonyl reductase gene,CRB3,lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.
Host	Mouse
Immunogen	Recombinant full length Human CBR1.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P16152
Uniprot	P16152
Weight	Predicted band size:30KDaObserved band size:30KDa

Description	Product: Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol. Specificity: CBR1 mAb detects endogenous levels of CBR1 protein.
Purity	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, ICC

Description

WB ; ICC

Dilution

WB	1:1000
ICC	1:100

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11309062	MB0121	50µl	$234.89		Add to Cart
BHA11309062	MB0121	100µl	$368.22		Add to Cart

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