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Home / Primary Antibodies / IHC Antibodies

Anti-ELOA Antibody BHA11308441

SKU : BHA11308441

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Mfr.No.	BS8635
Alternative Names	Transcription elongation factor B polypeptide 3 ; RNA polymerase II transcription factor SIII subunit A1 ; SIII p110 ; Elongin A ; EloA ; Elongin 110 kDa subunit ; TCEB3
Antigen	ELOA
Categories	Primary Antibodies
Chromosome Location	1p36.11
Clonality	polyclonal
Description	Individuals harboring germline mutations in the tumor suppressor gene von Hippel-Lindau (VHL) exhibit an increased susceptibility to a variety of tumors including renal carcinoma, hemangio-blastoma of the central nervous system and pheochromo-cytoma. The Elongin (SIII) complex has been identified as the functional target of the VHL protein. Elongin (SIII) is a heterotrimer composed of a transcriptional active subunit designated Elongin A and two regulatory subunits designated Elongin B and Elongin C. VHL functions by binding to the Elongin B and C subunits, inhibiting the transcriptional efficacy of the Elongin (SIII) complex. The VHL protein migrates with an apparent molecular weight of 38 kDa. The Elongin A subunit is 773 amino acids in length and has an apparent molecular weight of 110 kDa, while Elongin B and C are 18 kDa and 15 kDa proteins, respectively.
Host	Rabbit
Immunogen	Recombinant full length Human Elongin A1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q14241
Uniprot	Q14241
Weight	90kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: Elongin A1 polyclonal antibody detects endogenous levels of Elongin A1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308441	BS8635	50µl	$234.89		Add to Cart
BHA11308441	BS8635	100µl	$368.22		Add to Cart

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