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Home / Primary Antibodies / Recombinant Antibodies

Anti-NDUFS4 Antibody BHA11308088

SKU : BHA11308088

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Mfr.No.	BS8179
Alternative Names	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial ; Complex I-18 kDa ; CI-18 kDa ; Complex I-AQDQ ; CI-AQDQ ; NADH-ubiquinone oxidoreductase 18 kDa subunit ; NDUFS4
Categories	Primary Antibodies
Chromosome Location	5q11.2
Clonality	polyclonal
Description	Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFS4 (NADH dehydrogenase (ubiquinone) Fe-S protein 4), also known as AQDQ or CI-18 (Complex I-18kDa protein), belongs to the Complex I NDUFS4 subunit family. NDUFS4 localizes to the matrix side of the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. Mutations in the gene encoding NDUFS4 can result in Complex I mitochondrial respiratory chain deficiency. Patients with this deficiency may exhibit cardiomyopathy, myopathy, liver failure and neurological disorders.
Host	Rabbit
Immunogen	Recombinant full length Human NDUFS4.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O43181
Uniprot	O43181
Weight	20 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: NDUFS4 polyclonal antibody detects endogenous levels of NDUFS4 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308088	BS8179	50µl	$234.89		Add to Cart
BHA11308088	BS8179	100µl	$368.22		Add to Cart

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