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Home / Primary Antibodies / Recombinant Antibodies

Anti-CHD2 Antibody BHA11308019

SKU : BHA11308019

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Mfr.No.	BS8087
Alternative Names	Chromodomain-helicase-DNA-binding protein 2 ; CHD-2 ; ATP-dependent helicase CHD2 ; CHD2
Categories	Primary Antibodies
Chromosome Location	15q26.1
Clonality	polyclonal
Description	The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD proteins alter gene expression by modifying chromatin structure,thereby altering access of the transcriptional machinery to its chromosomal DNA template. Chromodomain helicase DNA binding protein 2, also known as CHD2, is a member of the SNF2/RAD54 helicase family of chromatin remodeling and DNA-binding proteins (CDH proteins). Consisting of 1,828 amino acids, CHD2 is expressed in the nucleus and contains two chromo domains, a helicase ATP-binding domain and a helicase C-terminal domain. CHD2 is suggested to play a critical role in development, hematopoiesis and tumor suppression. Mutations in the gene encoding CHD2 may be the cause of glomerulopathy, proteinuria and significantly impaired kidney function. CHD2 exists as two alternatively spliced isoforms.
Host	Rabbit
Immunogen	Recombinant full length Human CHD2.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O14647
Uniprot	O14647
Weight	211 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CHD2 polyclonal antibody detects endogenous levels of CHD2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308019	BS8087	50µl	$234.89		Add to Cart
BHA11308019	BS8087	100µl	$368.22		Add to Cart

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