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Home / Primary Antibodies / Recombinant Antibodies

Anti-SSRP1 Antibody BHA11308106

SKU : BHA11308106

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Mfr.No.	BS8198
Alternative Names	FACT complex subunit SSRP1 ; Chromatin-specific transcription elongation factor 80 kDa subunit ; Facilitates chromatin transcription complex 80 kDa subunit ; FACT 80 kDa subunit ; FACTp80 ; Facilitates chromatin transcription complex subunit ; SSRP1 ; Recombination signal sequence recognition protein 1 ; Structure-specific recognition protein 1 ; hSSRP1 ; T160 ; SSRP1 ; FACT80
Antigen	SSRP1
Categories	Primary Antibodies
Chromosome Location	11q12.1
Clonality	polyclonal
Description	Expression of protein-coding genes requires the association of specific transcription factors, RNA polymerase and various accessory factors (1). These accessory factors are distinguished as either histone acetyltransferases or ATP-dependent chromatin-remodeling enzymes, which include FACT (for facilitates chromatin transcription), and they facilitate transcription initiation on DNA packaged into chromatin. FACT is a chromatin-specific elongation factor required for transcription of chromatin templates, and it specifically interacts with nucleosomes and histone H2A/H2B dimers, to promote nucleosome disassembly upon transcription. FACT represents a complex between SPT16, a homologue of the Saccharomyces cerevisiae Spt16/Cdc68 protein, and the high-mobility group (HMG)-1-like protein structure-specific recognition protein-1 (SSRP-1). Similar to other (HMG) domain containing proteins, which are characterized by their ability to bend target DNAs, SSRP1 and the murine ortholog T160, physically interact with serum response factors (SRF) and function as positive co-regulatory proteins involved in modulating SRF-dependent gene expression .
Host	Rabbit
Immunogen	Recombinant full length Human SSRP1.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q08945
Uniprot	Q08945
Weight	81 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: SSRP1 polyclonal antibody detects endogenous levels of SSRP1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC	1:50-1:200
IF	1:10-1:100

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308106	BS8198	50µl	$234.89		Add to Cart
BHA11308106	BS8198	100µl	$368.22		Add to Cart

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