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Home / Primary Antibodies / Recombinant Antibodies

Anti-BNIP3L Antibody BHA11308026

SKU : BHA11308026

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Mfr.No.	BS8100
Alternative Names	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like ; Adenovirus E1B19K-binding protein B5 ; B CL2/adenovirus E1B 19 kDa protein-interacting protein 3A ; NIP3-like protein X ; NIP3L ; BNIP3L ; BNIP3A ; BNIP3H ; NIX
Categories	Primary Antibodies
Chromosome Location	8p21.2
Clonality	polyclonal
Description	The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include Nip1, Nip2, Nip3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. Nip1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. Nip2 shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, Nip2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to Nip3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. Nip3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.
Host	Rabbit
Immunogen	Recombinant full length Human BNIP3L.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O60238
Uniprot	O60238
Weight	24 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: BNIP3L polyclonal antibody detects endogenous levels of BNIP3L protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308026	BS8100	50µl	$234.89		Add to Cart
BHA11308026	BS8100	100µl	$368.22		Add to Cart

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