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Home / Primary Antibodies / Recombinant Antibodies

Anti-ZMYND11 Antibody BHA11308055

SKU : BHA11308055

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Mfr.No.	BS8134
Alternative Names	Zinc finger MYND domain-containing protein 11 ; Adenovirus 5 E1A-binding protein ; Bone morphogenetic protein receptor-associated molecule 1 ; Protein BS69 ; ZMYND11 ; BRAM1 ; BS69
Categories	Primary Antibodies
Chromosome Location	10p15.3
Clonality	polyclonal
Description	The adenovirus E1A gene products are nuclear phosphoproteins with the ability to transactivate other adenovirus genes. BS69 specifically interacts with adenovirus 5 E1A and inhibits transactivation by the 289R E1A protein. BS69 interacts with the co-repressor N-CoR through an essential MYND domain in the carboxy terminus of N-CoR. BS69 also inhibits the transcriptional activity of c-Myb. During oncogenesis, this BS69/Myb regulatory circuit maybe be a target for disruption . Another ubiquitously expressed member of the Myb gene family, b-Myb, also interacts with BS69 and N-CoR to function as a transcriptional repressor. BRAM1, a splice variant of BS69, binds specifically to bone morphogenetic protein type IA receptor (BMPR-IA). BRAM1 localizes to the cytoplasm of mammalian cells, while BS69 localizes to the cell nucleus . Unlike BS69, BRAM1 is unable to repress transcription .
Host	Rabbit
Immunogen	Recombinant full length Human ZMYND11.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q15326
Uniprot	Q15326
Weight	71 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: ZMYND11 polyclonal antibody detects endogenous levels of ZMYND11 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308055	BS8134	50µl	$234.89		Add to Cart
BHA11308055	BS8134	100µl	$368.22		Add to Cart

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