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Home / Primary Antibodies / IHC Antibodies

Anti-PTBP1 Antibody BHA11307496

SKU : BHA11307496

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Mfr.No.	BS7296
Alternative Names	57 kDa RNA binding protein PPTB 1 ; 57 kDa RNA binding protein PPTB1 ; 57 kDa RNA-binding protein PPTB-1 ; Heterogeneous nuclear ribonucleoprotein I ; Heterogeneous Nuclear Ribonucleoprotein Polypeptide I ; hnRNP I ; HNRNP-I ; HNRNPI ; HNRPI ; MGC10830 ; MGC8461 ; Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) ; Polypyrimidine Tract Binding Protein 1 ; Polypyrimidine tract binding protein ; Polypyrimidine tract-binding protein 1 ; pPTB ; PTB 1 ; PTB 2 ; PTB 3 ; PTB 4 ; PTB ; PTB T ; PTB1 ; PTB2 ; PTB3 ; PTB4 ; PTBP 1 ; PTBP1 ; PTBP1_HUMAN ; PTBT ; RNA Binding Protein
Antigen	PTBP1
Categories	Primary Antibodies
Chromosome Location	19p13.3
Clonality	polyclonal
Description	This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
Host	Rabbit
Immunogen	Recombinant full length Human PTBP1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P26599
Uniprot	P26599
Weight	; 57 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: PTBP1 polyclonal antibody detects endogenous levels of PTBP1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307496	BS7296	50µl	$234.89		Add to Cart
BHA11307496	BS7296	100µl	$368.22		Add to Cart

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