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Home / Primary Antibodies / Recombinant Antibodies

Anti-MKL1 Antibody BHA11307216

SKU : BHA11307216

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Mfr.No.	BS72392
Alternative Names	MKL/myocardin-like protein 1 ; Megakaryoblastic leukemia 1 protein ; Megakaryocytic acute leukemia protein ; Myocardin-related transcription factor A ; MRTF-A ; MKL1 ; KIAA1438 ; MAL
Categories	Primary Antibodies
Chromosome Location	22q13.1-q13.2
Clonality	polyclonal
Description	Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factor A (MRTF-A), also known as MKL1, interacts with SRF and stimulates its transcriptional activity.
Host	Rabbit
Immunogen	Recombinant protein of human MKL1
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q969V6
Uniprot	Q969V6
Weight	145 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: MRTF-A polyclonal antibody detects endogenous levels of MRTF-A protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307216	BS72392	50µl	$234.89		Add to Cart
BHA11307216	BS72392	100µl	$368.22		Add to Cart

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