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Home / Primary Antibodies / Recombinant Antibodies

Anti-GREM1 Antibody BHA11307103

SKU : BHA11307103

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Mfr.No.	BS72283
Alternative Names	C15DUPq ; CKTSF1B1 ; CRAC1 ; CRCS4 ; DAND2 ; DRM ; DUP15q ; GREMLIN ; HMPS ; HMPS1 ; IHG-2 ; MPSH ; PIG2
Antigen	GREM1
Categories	Primary Antibodies
Chromosome Location	15q13.3
Clonality	polyclonal
Description	This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host	Rabbit
Immunogen	Recombinant protein of human GREM1
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O60565
Uniprot	O60565
Weight	15kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: GREM1 polyclonal antibody detects endogenous levels of GREM1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307103	BS72283	50µl	$234.89		Add to Cart
BHA11307103	BS72283	100µl	$368.22		Add to Cart

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