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Home / Primary Antibodies / Recombinant Antibodies

Anti-RASGRP1 Antibody BHA11306559

SKU : BHA11306559

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Mfr.No.	BS71758
Alternative Names	V ; RASGRP ; hRasGRP1 ; CALDAG-GEFI ; CALDAG-GEFII
Categories	Primary Antibodies
Chromosome Location	15q14
Clonality	polyclonal
Description	This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
Host	Rabbit
Immunogen	Recombinant protein of human RASGRP1
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O95267
Uniprot	O95267
Weight	Predicted band size: 90 kDaObserved band size: Refer to Figures

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: RASGRP1 polyclonal antibody detects endogenous levels of RASGRP1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:1000-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11306559	BS71758	50µl	$234.89		Add to Cart
BHA11306559	BS71758	100µl	$368.22		Add to Cart

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