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Home / Primary Antibodies / Recombinant Antibodies

Anti-ULBP2 Antibody BHA11305928

SKU : BHA11305928

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Mfr.No.	BS71139
Alternative Names	N2DL2 ; RAET1H ; NKG2DL2 ; ALCAN-alpha
Categories	Primary Antibodies
Chromosome Location	6q25.1
Clonality	polyclonal
Description	Cytomegalovirus UL16 binding proteins, known as ULBPs, are GPI-linked glycoproteins that belong to the extended MHC class I family. ULBP proteins are ligands for the activating receptor, NKG2D/DAP10, which causes lymphocyte activation, resulting in the secretion of cytokines, such as interferon-gamma and tumor cell lysis. ULBPs stimulate cytokine and chemokine production from NK cells, CD8 alpha/beta T cells, and gamma/delta T cells. UL16, binds to three of the five known ligands for human NKG2D. UL16 is retained in the endoplasmic reticulum and cis-Golgi apparatus of cells and causes MICB to be similarly retained and stabilized within cells. Coexpression of UL16 markedly reduces cell surface levels of MICB, ULBP1, and ULBP2, and decreases susceptibility to natural killer cell-mediated cytotoxicity.
Host	Rabbit
Immunogen	Recombinant protein of human ULBP2.
Reactivity	Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9BZM5
Uniprot	Q9BZM5
Weight	27 kDa

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: ULBP2 polyclonal antibody detects endogenous levels of ULBP2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305928	BS71139	50µl	$234.89		Add to Cart
BHA11305928	BS71139	100µl	$368.22		Add to Cart

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