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Home / Primary Antibodies / IHC Antibodies

Anti-CTNNA1 Antibody BHA11305179

SKU : BHA11305179

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Mfr.No.	BS6976
Alternative Names	Catenin alpha-1 ; Alpha E-catenin ; Cadherin-associated protein ; Renal carcinoma antigen NY-REN-13 ; CTNNA1 ; Catenin-α1 ; Catenin α1 ; αE-catenin ; Catenin alpha-2 ; Alpha N-catenin ; Alpha-catenin-related protein ; CTNNA2 ; CAPR ; Catenin-α2 ; Catenin α2 ; αN-catenin
Antigen	CTNNA1
Categories	Primary Antibodies
Chromosome Location	5q31.2
Clonality	polyclonal
Description	α E-catenin (also designated α-catenin; cadherin-associated protein, alpha 1, 102kDa; and CAP102) plays a role in E-cadherin mediated cell-cell adhesion by linking E-cadherin to the cytoskeleton via β- or γ-catenin and Actin. α E-catenin connects cell-density-dependent adherens junctions with the developmental hedgehog pathway and may provide a negative feedback loop controlling the size of developing cerebral cortex. It is abundant in neuroepithelial precursor cells in the developing cortical ventricular zone of the brain, with reduced expression in the cortical plate. α E-catenin-vinculin interactions play a role in the assembly of the apical junction complex in epithelia. Catenins generally are thought to work as connectors that anchor E-cadherin to the cytoskeletal Actin bundle through the cadherin cytoplasmic domain. Dysfunction of this adhesion complex causes dissociation of cancer cells from primary tumor nodules, and is thus considered a contributing factor to metastasis.
Host	Rabbit
Immunogen	Recombinant full length Human Catenin-α1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P35221
Uniprot	P35221
Weight	100, 120kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: Catenin-α1 polyclonal antibody detects endogenous levels of Catenin-α1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IP

Description

WB ; IHC ; IP

Dilution

WB	1:500-1:2000
IHC	1:50-1:200
IP	1:50-1:100

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305179	BS6976	50µl	$234.89		Add to Cart
BHA11305179	BS6976	100µl	$368.22		Add to Cart

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