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Home / Primary Antibodies / Recombinant Antibodies

Anti-CXCR3 Antibody BHA11305191

SKU : BHA11305191

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Mfr.No.	BS6993
Alternative Names	C-X-C chemokine receptor type 3 ; CXC-R3 ; CXCR-3 ; CKR-L2 ; G protein-coupled receptor 9 ; Interferon-inducible protein 10 receptor ; IP-10 receptor ; CD183 ; GPR9 ; CXCR3
Categories	Primary Antibodies
Chromosome Location	Xq13.1
Clonality	polyclonal
Description	The CXC or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemo-attractants for neutrophils. The CXC family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 or SDF-1. SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes but not neutrophils. Receptors for the CXC family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB, CXCR-3 and fusin (variously referred to as LESTR or CXCR-4). CXCR-3, also known as IP-10/Mig receptor, mediates Ca++ mobilization and chemotaxis in response to the CXC chemo-kines IP-10 and Mig. CXCR-3 is highly expressed in IL-2-activated T lymphocytes, but not in resting T lymphocytes, B lymphocytes, monocytes or granulocytes.
Host	Rabbit
Immunogen	Recombinant full length Human CXCR-3.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P49682
Uniprot	P49682
Weight	40 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CXCR-3 polyclonal antibody detects endogenous levels of CXCR-3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305191	BS6993	50µl	$234.89		Add to Cart
BHA11305191	BS6993	100µl	$368.22		Add to Cart

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