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Home / Primary Antibodies / Recombinant Antibodies

Anti-COCH Antibody BHA11305153

SKU : BHA11305153

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Mfr.No.	BS6944
Alternative Names	Cochlin ; COCH-5B2 ; COCH ; COCH5B2 ; UNQ257 ; PRO294
Antigen	COCH
Categories	Primary Antibodies
Chromosome Location	14q12
Clonality	polyclonal
Description	Cochlin is a secreted protein encoded by the coagulation factor C homology (COCH) gene, a cochlear gene. It constitutes 70% of the inner ear proteins and is classified into three glycosylated isoforms: p63s, p44s and p40. Cochlin contains an N-terminal LCCL domain and two von Willebrand factor A-like domains. Mutations in the COCH gene cause DFNA9, an autosomal dominant nonsyndromic auditory and vestibular dysfunction disorder, as a result of either an amino acid deletion in the LCCL domain or missense substitutions. Microfibrillar deposits accumulate in the inner ear of individuals with DFNA9 and these deposits may contain the Cochlin protein. Cochlin is a target antigen for autoimmune sensorineural hearing loss.
Host	Rabbit
Immunogen	Recombinant full length Human COCH.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O43405
Uniprot	O43405
Weight	59 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: COCH polyclonal antibody detects endogenous levels of COCH protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC/IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305153	BS6944	50µl	$234.89		Add to Cart
BHA11305153	BS6944	100µl	$368.22		Add to Cart

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