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Home / Primary Antibodies / IHC Antibodies

Anti-CLDN1 Antibody BHA11305034

SKU : BHA11305034

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Mfr.No.	BS6778
Alternative Names	Claudin-1 ; CLD1 ; ILVASC ; SEMP1 ; Claudin1 ; CLDN1 ; UNQ481/PRO944
Categories	Primary Antibodies
Chromosome Location	3q28
Clonality	polyclonal
Description	The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tigh junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.
Host	Rabbit
Immunogen	Recombinant full length Human Claudin 1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O95832
Uniprot	O95832
Weight	22 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CLDN1 polyclonal antibody detects endogenous levels of CLDN1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305034	BS6778	50µl	$234.89		Add to Cart
BHA11305034	BS6778	100µl	$368.22		Add to Cart

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