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Home / Primary Antibodies / Recombinant Antibodies

Anti-MIF Antibody BHA11304954

SKU : BHA11304954

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Mfr.No.	BS6665
Alternative Names	Macrophage migration inhibitory factor ; Glycosylation-inhibiting factor ; GIF ; L-dopachrome isomerase ; L-dopachrome tautomerase ; Phenylpyruvate tautomerase ; MIF ; GLIF ; MMIF
Categories	Primary Antibodies
Chromosome Location	22q11.23
Clonality	polyclonal
Description	Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor α (TNFα), interleukin-1 (IL-1) and interferon-γ (IFN-γ). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.
Host	Rabbit
Immunogen	Recombinant full length Human MIF.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P14174
Uniprot	P14174
Weight	13 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: MIF polyclonal antibody detects endogenous levels of MIF protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304954	BS6665	50µl	$234.89		Add to Cart
BHA11304954	BS6665	100µl	$368.22		Add to Cart

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