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Home / Primary Antibodies / Recombinant Antibodies

Anti-SIRT1 Antibody BHA11304829

SKU : BHA11304829

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Mfr.No.	BS6494
Alternative Names	NAD-dependent protein deacetylase sirtuin-1 ; hSIRT1 ; Regulatory protein SIR2 homolog 1 ; SIR2-like protein 1 ; hSIR2 ; SirtT1 75 kDa fragment ; 75SirT1 ; SIRT1 ; SIR2L1
Antigen	SIRT1
Categories	Primary Antibodies
Clonality	polyclonal
Description	NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. Serves as a sensor of the cytosolic ratio of NAD+/NADH which is altered by glucose deprivation and metabolic changes associated with caloric restriction.
Host	Rabbit
Immunogen	Recombinant full length Human SIRT1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO

Swissprot	Q96EB6
Uniprot	Q96EB6
Weight	82, 120 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: SIRT1 polyclonal antibody detects endogenous levels of SIRT1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IP

Description

WB ; IHC ; IP

Dilution

WB	1:500-1:2000
IHC	1:50-1:200
IP	1:50-1:100

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304829	BS6494	50µl	$234.89		Add to Cart
BHA11304829	BS6494	100µl	$368.22		Add to Cart

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