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Home / Primary Antibodies / Recombinant Antibodies

Anti-CDKN1A Antibody BHA11300114

SKU : BHA11300114

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Mfr.No.	AP0713
Alternative Names	Cyclin-dependent kinase inhibitor 1 ; CDK-interacting protein 1 ; Melanoma differentiation-associated protein 6 ; MDA-6 ; CDKN1A ; CAP20 ; CDKN1 ; CIP1 ; MDA6 ; PIC1 ; SDI1 ; WAF1
Categories	Primary Antibodies
Chromosome Location	6p21.2
Clonality	polyclonal
Description	It is now well established that cyclins play a positive role in promoting cell cycle transitions via their ability to associate with and activate their cognate cyclin-dependent kinases (Cdks). Cdk2 associates with cyclins A, D and E, and has been implicated in the control of the G1 to S phase transition in mammals. A novel Cdk-interacting protein, designated p21, Cip1 or WAF1, has been identified in cyclin A, cyclin D1, cyclin E and Cdk2 immunoprecipitates. p21 is a potent, tight-binding inhibitor of Cdks and can inhibit the phosphorylation of Rb by cyclin A-Cdk 2, cyclin E-Cdk2, cyclin D1-Cdk4 and cyclin D2-Cdk4 complexes. Expression of p21 is inducible by wildtype, but not mutant, p53. The mouse homolog of p21 is designated CAP20.
Host	Rabbit
Immunogen	Recombinant full length Human P21.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P38936
Uniprot	P38936
Weight	21 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: P21 (WQ1) polyclonal antibody detects endogenous levels of P21 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300114	AP0713	50µl	$190.44		Add to Cart
BHA11300114	AP0713	100µl	$294.44		Add to Cart

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