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Home / Proteins & Peptide

XIAP (Bir3), His-tag

SKU : BHP18200702

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Mfr.No.	75001
Description	Human x-linked inhibitor ofapoptosis (XIAP) Bir3 domain, alsoknown as IAP-like protein, API3, X-linkedIAP, and BIRC4, amino-acids 241 - 356(GenBank Accession No. NM_001167)with N-terminal His-tag, MW = 14.2 kDa,expressed in an E. coli expressionsystem.
Immunogen Region	241-356
Tag	N-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, 3 mM DTT and 20% glycerol
Species	Human
Application	Useful in binding and inhibition studies of Caspase 9, screening inhibitors, and selectivity profiling.
Notes	50 mM Tris-HCl, pH 7.4, 25 mM NaCl, 0.05% Tween-20, 0.01% BSA, 0.5 nM FAM-SMAC peptide. Incubate 30 minutes at room temperature. Fluorescence polarization is measured at exc 475 nm, em 528 nm. Avoid freeze/thaw cycles.
GenBank	NM_001167
Mw(kda)	14.2 kDa

Synonyms	XIAP, IAP-like protein, API3, X-linked IAP, BIRC4
Uniprot	P98170

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Nikolovska-Coleska, Z., et al., Anal Biochem. 2008 Mar 1;374(1):87-98. 2. Verhagen, A.M., et al., Cell Death Differ. 2007 Feb;14(2):348-57 3. Fulda, S., Vucic., D., Nat Rev Drug Discov. 2012 Feb 1;11(2):109-24

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200702	75001	50 ug	$385		Add to Cart

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